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7 mindbodygreen Supplements for Perimenopause, Menopause, and Beyond

I remember all too well how disorienting and frustrating my 40s were. One moment I was sailing through my day, and the next, I was flushed, forgetful, or wondering why I was bone-tired even after a full night’s sleep. Some days, I barely recognized my own body.

Sound familiar? You may be experiencing the changes that often occur as menopause approaches. It was only after countless hours of research that I realized the remarkable nature of this transition and how much support I’d need to get through it. 

mindbodygreen makes this easier.

For over a decade, mindbodygreen has partnered with leading functional medicine practitioners and hormone specialists to create science-backed supplement formulations to support you through menopause and beyond. 

The following seven supplements were chosen based on the following criteria:

  • Strong scientific foundation: Each supplement is formulated with research-backed ingredients proven effective during hormonal transitions.
  • Targeted symptom relief: The formulations target the most common and impactful symptoms women experience.
  • Optimal formulation quality: Bioavailable forms and synergistic ingredient combinations maximize effectiveness in every formula.

Taken as part of a doctor-approved daily regimen, they can help you feel more like yourself again.

1. ultimate multivitamin+

Best for: Hair, skin, nails, and whole body support
Current cost: $70 one-time purchase, $59 or less with subscription

As you enter perimenopause, you might start to notice thinning hair, brittle nails, or duller skin, and changes in energy. This multivitamin fills common nutritional gaps with key vitamins and minerals that support your energy and natural beauty.

How it helps: This formula uses easily absorbed nutrients to help stabilize your energy while nourishing hair, skin, and nails. *

Foundation: Multivitamins provide nutritional insurance during periods of increased physiological stress. The bioavailable forms used in this formula ensure optimal absorption, particularly when digestive efficiency may be compromised.

2. sleep support+

Best for: Sleep disruptions, night sweats, and restless nights
Current cost: $60 one-time purchase, $49 or less with subscription

Sleep issues are prevalent during menopause. Studies show that 56% of perimenopausal women sleep less than the recommended seven hours per night. Research also indicates that sleep problems affect 40–60% of menopausal women, with 26% experiencing severe sleep issues.

Quality sleep becomes even more challenging during menopause, but sleep support+ offers a melatonin-free solution. This formula combines magnesium bisglycinate, jujube, and PharmaGABA® to help you fall asleep faster and stay asleep longer.

How it helps: The three clinically studied ingredients work together to calm your nervous system naturally. Magnesium bisglycinate is particularly beneficial during menopause as it supports nervous system regulation and can help you feel more at ease. *

Foundation: Magnesium deficiency is common in menopausal women and directly impacts sleep quality. The bisglycinate form offers superior absorption and gentler digestive tolerance compared to other magnesium forms.

3. vitamin D3 potency+

Best for: Bone density concerns, low mood, and immune support
Current cost: $30 one-time purchase, $25 or less with subscription

Sleep issues are prevalent during menopause. Studies show that 56% of perimenopausal women sleep less than the recommended seven hours per night. Research also indicates that sleep problems affect 40–60% of menopausal women, with 26% experiencing severe sleep issues.

Quality sleep becomes even more challenging during menopause, but sleep support+ offers a melatonin-free solution. This formula combines magnesium bisglycinate, jujube, and PharmaGABA® to help you fall asleep faster and stay asleep longer.

How it helps: The three clinically studied ingredients work together to calm your nervous system naturally. Magnesium bisglycinate is particularly beneficial during menopause as it supports nervous system regulation and can help you feel more at ease. *

Foundation: Magnesium deficiency is common in menopausal women and directly impacts sleep quality. The bisglycinate form offers superior absorption and gentler digestive tolerance compared to other magnesium forms.

4. omega-3 potency+

Best for: Heart, brain, joint, eye, and immune health
Current cost: $60 one-time purchase, $50 or less with subscription

Research shows that 60–67% of women experience cognitive difficulties during the menopausal transition. This includes memory problems, difficulty concentrating, and trouble finding words. Studies indicate that declining estrogen levels can affect omega-3 fatty acid metabolism in the brain.

Additionally, women lose estrogen’s heart-protective benefits during menopause, putting them at increased risk for cardiovascular disease. This potent omega-3 formula delivers the right amount of crucial EPA and DHA fatty acids your body needs to function at its best.

How it helps: EPA and DHA fatty acids directly support brain cell membranes for clearer thinking and a stable mood. They also provide heart-protective benefits as estrogen’s benefits naturally decline. *

Foundation: Omega-3 fatty acids have extensive research supporting their anti-inflammatory properties and cardiovascular benefits. There’s emerging evidence for mood and cognitive support during menopause.

5. advanced probiotic+ with bloat support

Best for: Digestive health, bloating, regularity, and gut-brain connection
Current cost: $80 one-time purchase, $69 or less with subscription

Hormonal changes during menopause significantly impact digestive health. This often leads to increased bloating, irregular bowel movements, and changes in gut bacteria composition. The gut-brain connection also influences mood and stress response, making digestive health crucial for overall well-being.

This targeted probiotic formula features three clinically studied strains that specifically address bloating, gas, and digestive discomfort, supporting overall gut health.

How it helps: These specific strains work to rebalance your gut microbiome, reducing uncomfortable bloating. They support the gut-brain connection that influences mood and stress response during menopause. *

Foundation: The gut microbiome changes significantly during menopause. Targeted probiotic supplementation can help restore balance and reduce digestive symptoms.

6. creatine with taurine+

Best for: Muscle loss, brain fog, and faster recovery
Current cost: $65 one-time purchase, $55 or less with subscription

Women have 70–80% lower creatine stores than men, and these levels naturally decline with age. This makes supplementation especially crucial during menopause. Additionally, women lose up to 8–10% of muscle mass each decade after 30, with even greater losses during menopause.

This innovative formula combines five grams of creatine monohydrate with two grams of taurine. It supports lean muscle mass and combats brain fog. Additionally, research shows that creatine supplementation significantly improves memory and cognitive performance.

How it helps: Creatine provides rapid energy to both muscles and brain cells, helping preserve muscle mass and enabling faster workout recovery. The added taurine supports cellular hydration, reduces bloating, and enhances mental clarity. *

Foundation: Emerging research in postmenopausal women shows promise for creatine supplementation, particularly when combined with resistance training. This formula provides a practical daily dose with added taurine for enhanced benefits.

7. organic greens detox+

Best for: Energy and detoxification support
Current cost: $65 one-time purchase, $55 or less with subscription

During menopause, your liver works harder to process changing hormone levels. Supporting natural detoxification pathways becomes increasingly important. At the same time, getting adequate nutrients from fruits and vegetables becomes more challenging when appetite and digestion change.

This comprehensive blend features sea vegetables, dark leafy greens, digestive enzymes, prebiotics, and probiotics all in one tablespoon. The organic formula includes hormone-balancing ingredients like sea vegetables, chlorella, spirulina, and botanical herbs like ginger and turmeric.

How it helps: Sea vegetables naturally support hormone balance and provide the essential minerals that are often depleted during menopause. The diverse blend of organic greens provides essential nutrients while the digestive enzymes and probiotics support gut health. *

Foundation: Individual components of this specific blend have evidence supporting hormonal health and detoxification. This formula provides comprehensive nutritional support that can be particularly beneficial if dietary intake becomes inconsistent.

Your Menopause Support Strategy

You don’t have to navigate menopause feeling like a shadow of your former self. These seven mindbodygreen supplements work synergistically to address the interconnected aspects of menopause. While every woman’s experience is unique, having this comprehensive toolkit can help you feel more prepared and supported during this natural transition.

Getting Started:

  • Start gradually: Begin with the ultimate multivitamin+ as your foundation, then add sleep support+ if sleep issues are your primary concern.
  • Build strategically: Add vitamin D3 potency+ and omega-3 potency+ next, as these address core health needs during menopause. Consider the remaining three based on your specific symptoms and goals.
  • Consistency matters: Most benefits develop over weeks to months of consistent use, so patience and regularity are key.
  • Listen to your body: Pay attention to how you feel and adjust timing or combinations as needed.

Your Journey to Feeling Like Yourself Again

The best menopause supplements from mindbodygreen offer a science-backed pathway to reclaiming your energy, mental clarity, and sleep during this transformative time.

Whether you start with just one supplement or build a comprehensive routine, you’re taking a decisive step toward supporting your body through this natural transition. Thousands of women have already discovered how the right nutritional support can transform the menopause experience.

mindbodygreen stands behind every product with a 30-day money-back guarantee. If you don’t feel a difference, simply return your unopened products for a full refund. You have nothing to lose except the symptoms that have been holding you back.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult a healthcare professional before starting any menopause supplement routine.

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